Post #1434: William and Mary COVID trend to 2/14/2022

 

Source:  Calculated from William and Mary COVID-19 dashboard.  Virginia new case rate calculated from Virginia Department of Health data and Census population estimates by single year of age.

This week’s new-case number was an unpleasant surprise.  The rate of new cases among students at the Williamsburg campus is now more than three times the rate for 18-24 year olds in Virginia as a whole.

Even with the understanding that W&M students may be more likely to get tested, this seems like a significant difference.  As importantly, while new cases are trending down in Virginia as a whole, they appear to be trending up at William and Mary.

This is also completely at odds with a superficial reading of William and Mary’s 2/15/2022 email to parents (Subject:  [parents-l] W&M COVID-19 Updates), where they state that:

 "Currently, many of these metrics are trending favorably, ... we are encouraged that we are in a much better position than we were in early- to mid-January."

That’s a weirdly ambiguous piece of text.  You have to stop and realize that by “we”, they meant the U.S.A., and not William and Mary in particular.  Return to campus didn’t occur until the end of January, and William and Mary’s metrics are trending unfavorably.

To me, to the extent that anyone continues to worry about the health consequences of COVID-19, this current increase seems to be well worth tracking.  New case rates are falling throughout the country, but not at William and Mary.

So, what’s the issue with W&M students that is not present in that age group for Virginia as a whole?

If I return to that 2/15/2022 email, and as with that line above, try to read past the ambiguities and try to read between the lines, I have a pretty good guess as to what the main problem is.  Emphasis mine:

"One of the data points that does appear to be different this spring is the number of individuals being identified as close contacts. Given the high transmissibility of the Omicron variant, I encourage you to socialize in small groups with your core friends and colleagues and to meet outdoors whenever possible. For those that would like them, faculty and staff may order masks from the facilities management warehouse and students may pick up additional masks from the Sadler Center information desk. "

When I step back from all that polite talk, and focus on “socialize” and “masks”, my best guess is that the problem now is the exact same problem they’ve had in the past.  Probably, students have gone back to holding unmasked parties. 

That was the issue at the first return-to-campus outbreak under COVID.  That was the issue for the St. Patrick’s day outbreak last year.  It would be completely unsurprising if that were the issue now.

That’s purely guesswork on my part, but all the pieces seem to fit.

But why the seemingly nonchalant attitude on the part of the William and Mary administration?

Return briefly to last year’s St. Patrick’s day outbreak (Post #1099).  I think everybody took that one fairly seriously.  That outbreak generated 120 new cases in 11 days, or a rate of 11 new cases per day.  So, the current rate of daily new cases is now roughly what it was during the St. Patrick’s Day outbreak last year.

But while the case count is about the same as St. Patrick’s Day 2021, the health risks are vastly lower. That’s due to vaccination plus a milder strain of COVID-19.  CDC data show that full vaccination remains roughly 80% effective at avoiding hospitalization from Omicron, and that vaccination plus booster is is about 90% effective.  (You’d have to download the data from the references on the CDC vaccine effectiveness web page to find that.)  On top of that, the crude hospitalization rate for Omicron is about one-third that of prior variants.  All told, that’s something like a (1/(.2 x . 33)) = 15-fold reduction in health risk, per case, compared to the situation last year.  (No one has the data on significant health risks other than hospitalization, but I would expect all significant risks to be reduced roughly in proportion to the hospitalization risk.)  And so, the current 12 cases per day presents about the same population health risk as one new case per day would have, around this time last year.

With that in mind, it now makes more sense that William and Mary is dancing around the issue of parties and masks, now, when they took a lot firmer stand during prior periods that had roughly the same daily new case.

Again, guesswork on my part.  I can’t read their minds as to why the wording regarding socializing and masks is now so oblique.  But it makes logical sense.

All I can say for sure is that the metrics at William and Mary are not trending favorably.  COVID-19 may be approaching endemic status in a handful of areas, but the William and Mary campus is not yet one of them.  The seems well worth keeping an eye on for a while longer yet.

FWIW, I’m now of the opinion that for your average boostered individual, the health risk from COVID-19 now, in Virginia, is no higher than the risk from typical seasonal flu (explained here or here).  So I’m not trying to be alarmist at all.  I don’t see a huge risk here.  I’d just like to see the counts at W&M going down, as they are everywhere else.

Post #1433: COVID-19 trend to 2/14/2022, maybe the beginning of a slowdown.

 

The U.S. now stands at 47 new COVID-19 cases per 100K population per day, down 81% from the peak.  Only two states remain above 100 per day (KY, ID).  The majority of states are below 50; five states are below 25 new cases per 100K per day (NY-NJ-CT, MD-DC).

Cases are down 39% in the past seven days, a bit slower than in the recent past.

As I said in recent posts, I think the decline in the official new case count is being exaggerated, probably as a result of the growing use of home testing using over-the-counter rapid tests.  As an alternative measure that should be unaffected by that, new COVID-19 hospitalizations are down 55% from the Omicron wave peak. Continue reading Post #1433: COVID-19 trend to 2/14/2022, maybe the beginning of a slowdown.

Post #1432: COVID-19 trend to 2/11/2022: Great news, the case counts are wrong.

 

The official count of U.S. new COVID-19 cases per 100K population per day now stands at 57, down 42% over the past seven days.  The U.S., unlike any other country, is seeing an extended, uniform, smooth decline in new case counts, with no slowdown in sight.

See caveat section below before you get too excited about that.

Continue reading Post #1432: COVID-19 trend to 2/11/2022: Great news, the case counts are wrong.

Post #1431: COVID-19 trend to 2/10/2022. The trend is good. Maybe too good. Revisiting the home-testing issue.

 

The U.S. now stands at 63 new COVID-19 cases per 100K per day, down 43 percent in the last seven days, and down almost three-quarters from the 1/16/2022 peak of the Omicron wave.

Just eight states remain about 100 cases / 100K population per day, and no states exceed 200.

So far, there is still no clear sign of any letup in the rate of descent.  That makes the U.S. experience unusual (possibly unique) by international standards. 

Could this lengthy, steady, and extremely rapid descent reported positive cases be a consequence of some sort of problem with the data, such as the rise of in-home testing?

Turns out, the answer to that is yeah, it just might.  Hospitalizations and deaths are not falling anywhere near as fast as reported cases.  Best guess, that only started to happen in early January.

Continue reading Post #1431: COVID-19 trend to 2/10/2022. The trend is good. Maybe too good. Revisiting the home-testing issue.

Post #1430: COVID-19 trend to 2/9/2022, Omicron nears flu-like risk for boostered individuals.

 

The U.S. now stands at an average of 70 new COVID-19 cases per 100K population per day.  That’s down 42% in the last seven days. No states are above 200 cases / 100K / day; 43 states are below 100.

The rate of decline is slowing, just a bit, but the rate of nuttiness remains constant.  Apparently, large swaths of America are shocked, shocked to find out that in response to low current risk and rapidly falling cases, governors of many states are dropping mask mandates.  E.g., this reporting, attributing mask mandate repeals to pandering politicians.  I wonder what they think the alternative would be?  Masks forever?

In fairness, much of the reporting has it right.  E.g., mandates fall as we approach normalityMandates are eased in response to lower infection and hospitalization numbers.

(And let me contrast dropping a mask mandate, where, with forethought, public health officials make some reasoned judgement regarding risk to the public, versus what we’re in the midst of doing in Virginia, which is initiating a free-for-all regarding in-school mask use, based on a fact-free campaign promise made by the governor about half-a-year ago, done with no reference to current conditions, no reasoned assessment of risk, and no clear guidance to schoolchildren.  We may eventually end up in the same maskless place.  That said, you can reach the ground floor of a skyscraper by walking down the stairs or jumping off the roof.  It’s smarter to have a government that takes the stairs.  We have one that can’t even acknowledge that the stairs exist.)

In this case, this blog was only a couple of days ahead of popular press reporting (Post #1426, 2/7/2022).  I’ll chalk up the short lead time to the speed with which Omicron cases counts continue to fall.

As a prelude to my next post, just how low are current risks?  CDC has now put up a very nice summary of what is known about vaccine effectiveness, as part of the CDC COVID data tracker.  Using (what I believe to be) clinical trials data, they estimate that the three-shot vaccine regimen is about 90% effective in preventing hospitalization from Omicron.

With that new information in hand, and accepting that as hard data, right now, the average vaccinated and boostered American faces about the same risk of hospitalization from Omicron as from flu in a typical flu season.  That’s how low risks have fallen, from the combination of low case severity, plummeting case numbers, and an effective three-shot vaccine regimen.

If that’s true, then why are COVID-19 hospitalizations (~12,000/day) higher than typical flu season hospitalizations (~2,100/day)?  Almost all the Omicron hospitalizations are among the unvaccinated, followed by the less-than-fully-boostered. Even now, this remains mainly a pandemic of the unvaccinated.

Finally, this is not new.  COVID-19 risk has temporarily dipped below typical flu risk before.  Your risk from COVID-19 falls to a low level every time COVID-19 new case counts get low enough.  Late last summer, case counts fell low enough that the average fully-COVID-vaccinated American faced lower hospitalization risk from COVID-19 than from typical seasonal flu.  The only difference now is that Omicron is much less virulent.  We now obtain that flu-equivalent risk level, for the fully vaccinated-and-boostered, at a fairly high Omicron case count.

Details follow.

Continue reading Post #1430: COVID-19 trend to 2/9/2022, Omicron nears flu-like risk for boostered individuals.

Post #1429: COVID-19 trend to 2/8/2022: Steady trend, continued rise of son-of-Omicron, and better the devil you know than the devil you don’t.

 

New COVID-19 cases continue to fall in the U.S. We’re now down to 74 new cases per 100K population per day.  The 7-day rate of decline is 44%, not materially different from yesterday’s 45%.

Data source for this and other graphs of new case counts:  Calculated from The New York Times. (2021). Coronavirus (Covid-19) Data in the United States. Retrieved 2/9/2022, from https://github.com/nytimes/covid-19-data.”  The NY Times U.S. tracking page may be found at https://www.nytimes.com/interactive/2020/us/coronavirus-us-cases.html

My gut reaction to today’s new data is that we’d passed the point of most rapid descent, and that the rate of decline will now begin to taper off, as we have seen in other countries.  As far as I can tell, there is no objective information to support that.

Here are the ten states that have led the way in the U.S. Omicron wave, plotted in logs so that a constant percentage decline shows as a straight line.  If the ends of those lines are bending toward flat, it’s a pretty subtle effect so far.

 

If there is a dark cloud on the near-term horizon, it’s the BA.2 variant (a.k.a., son-of-Omicron).  The CDC “Nowcast” projection pegs this at 3.6% of all U.S. cases, as of the week ended 2/5/2022.

Source:  CDC COVID data tracker, accessed 2/9/2022.

You might reasonably say, what’s the big deal?  BA.2 doesn’t appear to be any more virulent than Omicron, but it is more easily transmitted.  Original estimates were that it was about 50% more transmissible than Omicron, but more recent estimates put it closer to one-third more infectious than Omicron (reference).  Results from both Denmark and the U.K. appear to agree on that figure (reference).  If it becomes the prevalent strain, that will result in just so many more infections, all other things equal, and slow down our presumed “return to normalcy”.

Well worth noting, the CDC “Nowcast” model shows this strain’s share tripling every week.  On the one hand, you have to take that with a grain of salt, given the small numbers and the uncertainties involved.  On the other hand, if those projections are right, and accounting for the timing of the CDC data (that 3.6 figure would have been reached somewhere around 2/2/2022, BA.2 would be come the dominant strain in the U.S. approximately 2/19/2022, or ten days from today.  But weigh that fear-mongering against the observation that the growth of BA.2 has been all over the map, in various European countries, and that no country actually saw its share of BA.2 grow that rapidly.  My guess, based on European growth rates, is that this preliminary “Nowcast” estimate likely overstates the true rate of growth. 

The fact remains that BA.2 took over Denmark in a matter of weeks, but so far it remains a minor issue in most European countries.  Coincidence or not, it’s worth noting that Denmark still hasn’t reached a clear peak in its Omicron wave, despite having started that wave before the U.S. did.  Draw what conclusions you will from that sample of one.

Source:  Johns Hopkins University via Google Search

Finally, there is a bright side to transitioning from pandemic to endemic with as infectious a variant as possible, as long as that variant is relatively benign.  There’s no guarantee what the next new variant will bring.  Maybe the next one will be as virulent as Delta, or worse.  But that won’t matter unless that new variant is better able to spread better than the reigning champion, which will be either Omicron or son-of-Omicron.  The tougher those are to beat, from an infectiousness standpoint, the less likely we are to have some new and possibly far more virulent strain of COVID-19 take over.

It is truly a case of better the devil you know than the devil you don’t.  Looks like we will probably be able to deal with Omicron OK.  Plausibly we can deal with BA.2 OK.  Both owing to their much-reduced infectiousness and the ability of a booster shot to provide significant protection.  It’s probably better if we can stick with this variant as our endemic COVID-19, rather than roll the genetic dice and face something new.

Post #1428: COVID-19 trend at William and Mary through 2/7/2022

 

I’m going to continue to track Omicron for a while longer yet, at William and Mary.  William and Mary is only updating their data weekly so I guess I’ll post once a week, if there’s anything to write about.

I doubt that many will read these posts.  Most  W&M parents found out about this blog via a W&M-moderated Facebook group.  The moderators of that group have banned discussion of COVID-19, so I suspect that most on that group will never get back to this blog.

Enough said.  Most of the value-added here is that I keep track of the historical data.  That’s not available on the W&M COVID dashboard.

Based on two weeks of data, the new case rate at William and Mary seems fairly steady at 5 to 7 newly-diagnosed COVID-19 cases per day.

That most recent rate of 7-per-day translates to roughly 100 new cases per 100K students per day.

Contrast to Virginia as a whole:  That’s just a touch higher than the rate for 18-24 year olds in Virginia as a whole, which I estimate to be 77 / 100K / day, for the seven days ending 2/7/2022, based on Virginia Department of Health data.

Contrast to last semester:  That’s maybe four times higher than the peak post-move-in rate last semester.  After the initial post-return-to-campus wave had died off, the highest rate observed was 11 new cases in the week ending 12/10/2021.  That’s under 2 per day on average:

That said, Omicron has a much lower average severity than the Delta variant that was prevalent at the end of last semester.  For example, looking at the Virginia data, if I date the start of the Omicron wave to roughly 12/17/2021, then so far there have been zero deaths in the 18-24 age bracket, from Omicron, in the whole of Virginia.

If I had to sum it up, I would say two things.

First, there does appear to be some need for further vigilance.  COVID-19 has not disappeared from the campus.  That 100 cases per 100K per day rate is high by historical standards.  And I need to remind myself that these numbers didn’t just happen.  The relatively high new case rate occurred in an environment with fairly stringent COVID-19 hygiene in place.

That said, the rate at William and Mary isn’t much different from the rate for Virginians age 18-24 as a whole.  And once you factor in the much lower average severity per case, the health impact of the current case rate probably isn’t much different from the impact of Delta at the end of last semester.

In any case, the numbers are up from last year.  I see that as no cause for alarm, but no clear justification to relax, either.

Finally, I should note the obvious:  Pre-return testing seems to work pretty well at preventing a big return-to-campus outbreak.  This isn’t exactly a controlled experiment, but the one semester when W&M didn’t do pre-return testing, they ended up with a large number of active cases on campus, as shown in the last chart above.  The semesters when pre-return testing was required, that didn’t happen.

Post #1427: COVID-19 trend to 2/7/2022, linear descent continues

 

The U.S. is now at 78 new COVID-19 cases per 100K population per day.  That’s down 45 percent over the past seven days.  Since late January, that number has fallen by a more-or-less steady 10 cases per day.

Cases have now fallen by more than two-thirds since the 1/16/2022 peak of the Omicron wave.

Continue reading Post #1427: COVID-19 trend to 2/7/2022, linear descent continues

Post #1426: Nobody’s going to tell you when to stop wearing a mask. And, yet a third way to triangulate Omicron risk versus flu risk.

 

Let me start with an anecdote.

I went to two different farmers’ markets over the weekend.  These were open-air markets, sparsely attended.   And it was a breezy day, to boot.

In neither case did I think there was any reason whatsoever to wear a mask.  In both cases, I ended up wearing a mask.  Not because I thought it made sense, but because I wanted to fit into the crowd.  In both cases, the overwhelming majority of people in the marketplace were masked.

I’ve now gone full circle on pandemic mask use.  Early on, I couldn’t fathom why people weren’t using face masks.  Now, at least in some cases, I can’t fathom why they are.

In today’s news, I see that two East Coast Democratic governors have set a rough timetable for rolling back K-12 school mask mandates (per this reporting.)  This is in response to the declining new case counts for Omicron.  Right now, it looks like both of them are shooting for a March end of their respective school mask mandates.

In my humble opinion, that’s how it should be done.  They are accepting responsibility for this key part of school safety during the pandemic and they are actively managing it.  They are planning an orderly transition from masked to non-masked in-person K-12 instruction, based on what I hope are public health objectives.  In any case, for this group activity we call school, everyone in the group will be given the same signals regarding mask use, and when it’s time to take off the masks, everyone can be assured that the decision was done with some forethought as to the common risks involved in that.

This is good, if only because this approach avoids chaos and strife.  Within the large-group activity we call public school, everyone will get the same set of instructions.

Contrast this with the Virginia approach, where the Governor took no ownership at all over this key school safety issue.  Instead of managing the transition for the benefit of all, he issued an executive order to create individual parental-based exceptions to local mask mandates.  It allowed parents to exempt their children, one-by-one, based on their opinions (i.e., political leanings) rather than any public health criteria for the student body as a whole.  As an extra added bonus, it fairly clearly conflicted with existing Virginia statute, and as a result it has now ended up in court.

Which is bad, unless generating chaos and strife is part of your political agenda.

At any rate, because K-12 school is a group activity, run by the government, there likely will be some form of guidance in most places.  Some sort of mask use guidance.  If only because in most places, somebody responsible is supposed to be looking out for the health and welfare of the students as a whole.

We adults are not so lucky.  We’re each going to have to make our own individual decisions about mask use.  And as far as I can see, so far, that’s going to be based on the same amorphous social norms that governed masking up in the first place.  To the extent that dropping the masks will be enforced, it’ll be through peer pressure, not through any explicit advice from any government agency.

In short, as an adult, nobody’s going to tell you that masks are no longer needed. 

Not in the U.S, at any rate.  Other countries seem to be testing the waters for treating Omicron like seasonal flu, e.g., Spain.  But here in the U.S., I doubt the CDC is ever going to come out and say that masks should no longer be used.


Yet a third way to compare Omicron risk versus typical flu risk:  Brief background.

Let me not belabor this.  This is the third in a series of posts that asks the following question:

How low does the U.S. Omicron case load need to get, before the risk posed by Omicron is no higher than that posed by typical seasonal flu?

In Post #1400-3, I did the crude calculation for all persons pooled together, and came up with 16 new cases per 100K population per day.  That calculation was absolutely straightforward and easy to check.

In Post #1400-4, I refined that by generating a separate estimate for the boostered population alone.  That gave me a benchmark of 40 new COVID-19 cases per 100K population per day.   The number is higher because boosters provide significant protection against Omicrion.

But that calculation was anything but transparent.  And it was an extremely conservative estimate, in that I only account for the impact of vaccine and booster on the likelihood of getting infected, not on any further reduction in hospitalizations or deaths once infected.


A duh-piphany, or the most obvious way to compare Omicron risk to flu risk.

The main point of this exercise is to compare the risk of hospitalization or death under Omicron, to hospitalization or death from seasonal flu.

In which case, why don’t I .. uh … just compare those rates directly?  If I want to compare them based on deaths and hospitalizations, then simply do that.  Tabulate Omicron hospitalization and death rates on a 100K population basis, and compare those to typical seasonal flu.

It’s an eclat d’oh.

I mean, when the Omicron hospitalizations per 100K gets down to the level of flu hospitalizations per 100K, then by definition, the average person’s risk of getting hospitalized for Omicron matches the risk of being hospitalized for flu.  No further calculation needed, unless you want to try to separate out the boostered, vaccinated, and un-vaccinated populations.

Disease burden of flu in terms of deaths and hospitalizations per day and per 100K population.

I want to compare Omicron risk to risk from flu on a typical day during “flu season”.

The first issue is that I could not find any hard-and-fast CDC definition of flu season.  It’s just defined as the months — typically winter through early spring — around the peak of this curve.  Typically, somewhere around five months out of the year.

Source:  Calculated from CDC burden of flu, 2017-2028 season, assuming 30M total symptomatic flu cases for the entire year.

I’m going to define “flu season” as those weeks with an estimated 500K symptomatic flu cases or more.  In the example above, “flu season” lasted 18 weeks, and accounted for just about 70 percent of all flu cases during the year.

Source:  CDC disease burden of flu.

Based on that, and rounding the numbers, I come up with the following table comparing hospitalization and mortality rates for typical U.S. seasonal flu and the current levels of Omicron:

On a typical day in flu season, the U.S. sees 2100 flu hospitalizations.  Currently, with Omicron, we’re seeing an estimated 12,000 hospitalizations per day.  Based on that, for the U.S. as a whole, Omicron cases would have to fall to about 17.5 per day before the hospitalization risk from Omicron matched that of typical seasonal flu, for the average American.

(The mortality data are harder to use because a) deaths lag cases by a couple of weeks, and b) we’re only a few weeks past the Omicron peak.  So, compare to the current case count, we’re looking at far too many deaths.  And, accordingly, the ratio of current Omicron deaths to typical flu deaths is much larger than the current ratio of Omicron hospitalizations to typical flu hospitalizations.)

As you can see, all I have really done is re-create my first analysis.  Pooling all individuals together, you’ll have the same hospitalization risk for Omicron as for flu if Omicron gets down to 17.5 new cases / 100K / day.  (My initial analysis came out with 16 new cases / 100K / day).

The only value-added here is that this now directly translates into a COVID-19 daily hospitalization count.  That information is available on a timely basis for all states, via the CDC COVID data tracker.

For now, I’m just going to leave it at that.  Without being very precise about it, this is just another way of saying that at some point when Omicron cases get into the 10’s per 100K per day, your risk of severe illness from Omicron is no higher than your risk of severe illness from flu.

Tomorrow, I’ll take the final step in this process.  I’m going to combine and clean up all the results, and translate them into a set of state-level thresholds comparable to the data publicly available on the CDC COVID data tracker.  With that, you should be able to take those thresholds, bring up the CDC data from your state, and identify the time (if any) at which Omicron risk is below typical flu risk for the average resident, and for the fully-boostered resident, of your state.

Post #1425: COVID-19, last update for this data reporting week.

 

The U.S. COVID-19 case numbers continue to be surprisingly good.  The decline in new COVID-19 case counts continues to accelerate.  The U.S. now stands at 100 new cases per 100K population per day, down 40% in the past seven days.  Most states are now below 100 new cases / 100K / day.

Continue reading Post #1425: COVID-19, last update for this data reporting week.